SYNTHESIS OF CADMIUM ELENIDE DOPED TITANIUM DIOXIDE (TiO2) USING NON-HAZARDOUS CHEMICAL AND THEIR CHARACTERIZATION
Akshay Gautam¹, Prof. (Dr.) Satyavir Singh²
¹Research Scholar, School of Science, Glocal University, Mirzapur Pole, Saharanpur (U. P.)
²Research Supervisor, School of Science, Glocal University, Mirzapur Pole Saharanpur (U.P)
ABSTRACT
In the present work, Cadmium Selenide doped TiO2 nanomaterial is synthesized using novel procedure without using any hazardous or toxic chemicals, such as tri-n-octylphosphine (TOP), etc. Characterization of the synthesized material is carried out by UV–Visible absorption Spectroscopy and Fourier Transform infrared (FTIR). The UV–Vis absorption showed bandgap energy of about 2.8 eV in CdSe doped TiO2 is reported.
Keywords –
PHOTOCATALYTIC DEGRADATION OF METHYLENE BLUE USING CADMIUM SELENIDE DOPED TITANIUM DIOXIDE (TiO2) THEIR CHARACTERIZATION
Akshay Gautam¹, Prof. (Dr.) Satyavir Singh²
¹Research Scholar, School of Science, Glocal University, Mirzapur Pole, Saharanpur (U. P.)
²Research Supervisor, School of Science, Glocal University, Mirzapur Pole Saharanpur (U.P)
ABSTRACT
CdSe-TiO2 composites were created and tested for their ability to break down Methylene Blue solutions under visible light. The decomposition of the dye was assessed using UV-vis spectrophotometry. An enhancement in photocatalytic performance was noted, linked to heightened photoabsorption and the combined impact of CdSe-TiO2. The consistency of photocatalytic performance was also examined to assess the durability of the CdSe/TiO2 composites.
Keywords –
PORTRAYING THE FEMALE CHARACTERS IN ENGLISH LITERATURE
Manoj Shivaji Suryawanshi
Assistant Professor – Hod JSM College Alibag
ABSTRACT
The records of literary history document the changing status of women across many eras. Through thick and thin, women have persevered, gracefully enduring the scorn, contempt, and rejection that has marred their path. Some have tried to stop ladies from continuing their dangerous trek, but they have persisted nonetheless. The strong connection among modern women is the product of a long journey. The majority of creators are women. As far as our universe is concerned, women are the driving forces behind all progress. This research looks at how female characters in English literature are portrayed and how those depictions are influenced by social and cultural factors. This research looks at how female characters have developed through the ages, from ancient mythology to contemporary literature. It takes a close look at the literary works including women and how they are portrayed in terms of their roles, stereotypes, and control. The complex representation of female characters in literature is explored in this research through an examination of patriarchy, gender roles, and feminist critique. It shows how writing may reflect and challenge societal norms simultaneously.
Keywords – Female, English literature, Gender.
STABILITY OF THE FORMULATED TRANSDERMAL PATCH UNDER VARIOUS STORAGE CONDITIONS
¹Abhishek Kumar Sen and ²Dr. Fazlu Rehman
¹Research Scholar, Department of Pharmacy, The Glocal University, Mirzapur pole, Saharanpur, Uttar Pradesh
²Associate Professor, Department of Pharmacy, The Glocal University, Mirzapur pole, Saharanpur, Uttar Pradesh
ABSTRACT
This study investigates the stability of a formulated transdermal patch under different storage conditions. The patches were subjected to varying temperatures and humidity levels over a defined period. Physical appearance, drug content uniformity, and adhesive properties were assessed as stability indicators. Results indicate significant variations based on storage conditions, highlighting the importance of controlled environments in transdermal patch stability.
Keywords – Storage conditions, Accelerated aging, adhesive properties, Drug content uniformity, Controlled release.
CONTRACTOR PERFORMANCE: INSIGHTS INTO ENTREPRENEURIAL PRACTICES
¹Anil Kumar Khajuria and ²Dr. Sirna Santosh Kumar
¹Research Scholar, Department of Engineering & Technology, The Glocal University, Mirzapur pole, Saharanpur, Uttar Pradesh
²Assistant Professor, Department of Engineering & Technology, The Glocal University, Mirzapur pole, Saharanpur, Uttar Pradesh
ABSTRACT
The construction industry is a dynamic and complex field where contractor performance plays a critical role in the successful completion of projects. This research paper explores the intersection of contractor performance and entrepreneurial practices, aiming to uncover insights that can enhance the efficiency and effectiveness of contractors in the industry. By examining various entrepreneurial practices, including innovation, risk management, and strategic planning, this paper highlights how these practices impact contractor performance and the overall success of construction projects.
Keywords – efficiency, practices, contractor, projects, industry.
INVESTIGATION OF VIBRATION AND NOISE IN HYDROGEN DIRECT INJECTION (HDI) DIESEL ENGINES THROUGH VIBRATION SPECTRUM ANALYSIS AND OPTIMIZATION OF INJECTION PARAMETERS
¹Kaustubh Rajendra Kapdani and ²Dr. Nirmal Sharma
¹Research Scholar, Department of Engineering & Technology, The Glocal University, Mirzapur pole, Saharanpur, Uttar Pradesh
²Professor, Department of Engineering & Technology, The Glocal University, Mirzapur pole, Saharanpur, Uttar Pradesh
ABSTRACT
The literature on diesel engine performance reveals critical insights into combustion, noise, and vibration, particularly concerning alternative fuels and technological advancements. Calvo et al. (2005) emphasize improvements in diesel engines with direct injection but highlight ongoing challenges with noise and vibration, advocating for regulated approaches to manage these issues. Nag et al. (2022) explore the effects of exhaust gas recirculation (EGR) in a hydrogen-diesel dual-fuel system, finding that hydrogen reduces vibrations while EGR increases them, though their combination improves combustion noise and emissions. Jaikumar et al. (2020) investigate Mesua ferrea oil methyl ester (MFOME) blends in a VCR diesel engine, showing that blends, especially B20, enhance combustion properties and reduce noise compared to standard diesel. Ashok et al. (2020) assess lemon peel oil as a biofuel, finding it comparable to diesel in vibrations and noise, suggesting its viability as an alternative. Yildirim et al. (2018) use artificial intelligence, specifically Artificial Neural Networks (ANN) and Support Vector Machines (SVM), to forecast vibration, noise, and emissions in engines with biodiesel and hydrogen, with ANN proving more accurate. Satsangi and Tiwari (2018) focus on diesel-alcohol blends (diesohols) in gensets, noting improved noise and vibration at lower loads but decreased efficiency and increased hydrocarbon emissions with higher n-butanol concentrations. Wongchai et al. (2013) study the impact of hydrogen-diesel dual fuel on engine vibration, finding that higher hydrogen content reduces Average Peak Acceleration (APA), thus lowering vibrations.
Optimizing noise and vibration in Hydrogen Direct Injection Diesel (HDID) engines is essential for enhancing passenger comfort and vehicle longevity. HDID engines, combining diesel’s compression ignition with hydrogen direct injection, offer a promising path to cleaner and more efficient combustion. However, optimizing these engines poses significant challenges in managing noise and vibration. This research aims to minimize environmental impact while maintaining or improving engine performance and reliability, focusing on reducing noise and vibration levels. This involves identifying and mitigating sources of disturbances through a combination of experimental testing, computer modeling, and optimization techniques. Experimental testing uses engine dynamometers and vehicle testing to measure noise and vibration under various conditions, influenced by factors like injection timing and fuel-air ratio. Computational modeling provides predictions of noise and vibration based on operating conditions, aiding in engine design and control strategies. Effective techniques, including acoustic insulation, engine mounts, and vibration dampers, improve passenger comfort and vehicle durability. Ongoing research and innovation are crucial for harnessing the full potential of HDID engines, contributing to a greener and more sustainable energy future by addressing transportation’s environmental impacts.
Keywords – Hydrogen, Diesel Fuelled Engine, homogeneous charge compression ignition, diesel particulate filters, Hydrogen Direct Injection (HDI), Engine Optimization, Noise Reduction, Vibration Amplitudes, Vibration Analysis, Injection Timing, Vibration Spectrum Analysis, Frequency SpectrumAnalysis, Noise Pollution.
INNOVATIVE BLOCKCHAIN APPROACHES TO IOT SECURITY
¹Siddappa Gouda and ²Dr. Rajeev Yadav
¹Research Scholar, Department of Computer Science, The Glocal University, Mirzapur pole, Saharanpur, Uttar Pradesh
²Professor, Department of Computer Science, The Glocal University, Mirzapur pole, Saharanpur, Uttar Pradesh
ABSTRACT
The Internet of Things (IoT) represents a rapidly expanding ecosystem that integrates a multitude of devices into a connected network, enhancing convenience and efficiency across various domains. However, the proliferation of IoT devices introduces significant security challenges, including data breaches, unauthorized access, and system tampering. Blockchain technology, with its decentralized and immutable characteristics, offers promising solutions to address these security concerns. This paper explores innovative blockchain approaches to IoT security, examining how blockchain can be leveraged to enhance data integrity, privacy, and overall system resilience. We discuss various blockchain-based strategies, including smart contracts, decentralized identity management, and consensus mechanisms, and evaluate their effectiveness in securing IoT environments.
Keywords – Trust and Accountability, Scalability, Interoperability, Data Authentication, Regulatory Compliance.
STUDY ON SOME NOVEL STILBENES ANALOGUES AS ANTIPROLIFERATIVE AGENTS
¹Sheetal and ²Rahul Kumar Raj
¹Research Scholar, Department of Pharmacy, The Glocal University, Mirzapur pole, Saharanpur, Uttar Pradesh
²Associate Professor, Department of Pharmacy, The Glocal University, Mirzapur pole, Saharanpur, Uttar Pradesh
ABSTRACT
Malignant tumours are one of the world’s most serious hazards to human health, and the clinical prognosis is still insufficient. As a result, it is necessary to develop new therapeutic strategies for the improvement of presently available medications. There has been a lot of interest in using natural products or their derivatives to produce more effective hemotherapeutic drugs in recent decades. Natural chemicals having a stilbene backbone have shown to have promise anticancer activity in recent years, targeting a wide range of intracellular pathways. In view of that some new stilbene analogues were synthesized and screened them for antiangiogenic activity. Majority of the synthesised compounds exhibited considerable antiangiogenic activity. Antiangiogenic action was discovered to be affected by the size of the bridge substituent (on the Ethylene Bridge). Most active compounds of the antiangiogenic screening were further subjected for anticancer activity. Compound 5a showed maximum anticancer activity with % growth inhibition of 63.43 and 56.24 against HCT-116 and MCF-7 cell lines respectively. Further derivatization of these molecules will be helpful in the hopes of obtaining more selective and potent anticancer medicines.
Keywords – Stilbenes, Combretastatins, Antiangiogenic, Anticancer.
STUDIES ON SOME NOVEL (Z)-1-(5-CHLORO-FURAN-2-YL) 2-(4-NITROPHENYL) ETHENE ANALOGUES AS ANTIPROLIFERATIVE AGENTS
¹Sheetal and ²Rahul Kumar Raj
¹Research Scholar, Department of Pharmacy, The Glocal University, Mirzapur pole, Saharanpur, Uttar Pradesh
²Associate Professor, Department of Pharmacy, The Glocal University, Mirzapur pole, Saharanpur, Uttar Pradesh
ABSTRACT
Malignant tumours are one of the world’s most serious hazards to human health, and the clinical prognosis is still insufficient. As a result, it is necessary to develop new therapeutic strategies for the improvement of presently available medications. There has been a lot of interest in using natural products or their derivatives to produce more effective hemotherapeutic drugs in recent decades. Natural chemicals having a stilbene backbone have shown to have promise anticancer activity in recent years, targeting a wide range of intracellular pathways. In view of that some new stilbene analogues were synthesized and screened them for antiangiogenic activity. Majority of the synthesised compounds exhibited considerable antiangiogenic activity. Antiangiogenic action was discovered to be affected by the size of the bridge substituent (on the Ethylene Bridge). Most active compounds of the antiangiogenic screening were further subjected for anticancer activity. Compound 5a showed maximum anticancer activity with % growth inhibition of 63.43 and 56.24 against HCT-116 and MCF-7 cell lines respectively. Further derivatization of these molecules will be helpful in the hopes of obtaining more selective and potent anticancer medicines.
Keywords – Stilbenes, Combretastatins, Antiangiogenic, Anticancer.
EXISTENCE AND ROLE OF MEDICINAL HERBS TO DIABETIC TREATMENT
¹Maarishetty Suman Chandra and ²Jitendra K Malik
¹Research Scholar, School of Pharmacy, The Glocal University, Mirzapurpole, Saharanpur, Uttarpradesh, India
²Research Supervisor, School of Pharmacy, The Glocal University, Mirzapurpole, Saharanpur, Uttarpradesh, India
ABSTRACT
The traditional use of plants and their preparations in the treatment of diseases as a first medication in the past centuries indicates the presence of active components for specific targets in the natural material. Many of the tested plants in this study have been traditionally used in the treatment of Diabetes and associated symptoms in different cultural areas. In the last years, not only did the absolute number of people suffering from Diabetes mellitus increase from 108 Mio in 1980 to 422 Mio in 2014 but also the prevalence of this disease rose from 4.7 to 8.5% among adults during this time period worldwide (WHO, 2019). So this review helps the reader to understand the importance of various types of herbal and poly herbal formulations present traditionally which can be used to treat diabetes mellitus. India has about 45000 plant species and among them, several thousands have been claimed to possess medicinal properties. The present paper aims to review various plant species from Indian origin and their constituents, which have been used in the traditional system of medicine and have shown hypoglycaemic activity.
Keywords – Medicinal, herbs, diabetic, plants.
DIABETIC RETINOPATHY FOR THE TREATMENT OF DIABETIC COMPLICATIONS
¹Maarishetty Suman Chandra and ²Jitendra K Malik
¹Research Scholar, School of Pharmacy, The Glocal University, Mirzapurpole, Saharanpur, Uttarpradesh, India
²Research Supervisor, School of Pharmacy, The Glocal University, Mirzapurpole, Saharanpur, Uttarpradesh, India
ABSTRACT
The aim of this investigation is to address the existing evidence on antidiabetic effects of the selected plants (coccinia indica, basella rubra, hemidesmus indica, pterocarpus marsupium and swertia chirayita). The plants selected depending upon the literature available. The selected plant parts collected and authenticated, the plant parts were extracted using maceration method using methanol and ethanol as solvents, the prepared extracts screened for preliminary phytochemical screening and then the doses decided by performing acute toxicity studies. Diabetic retinopathy is a serious sight-threatening complication of diabetes. Diabetes interferes with the body’s ability to use and store sugar (glucose). The disease is characterized by too much sugar in the blood, which can cause damage throughout the body, including the eyes. Over time, diabetes damages small blood vessels throughout the body, including the retina. Diabetic retinopathy occurs when these tiny blood vessels leak blood and other fluids. This causes the retinal tissue to swell, resulting in cloudy or blurred vision.
Keywords – Diabetic, antidiabetic, Plants, retinopathy etc.
CONCEPTS FOR DATA STRENGTHENING IN CENTRAL COMPUTING
¹Mahesh Pal and ²Prof. Dr. Bhupendra Kumar
¹Research Scholar, Technology and Computer Science, The Glocal University, Mirzapurpole, Saharanpur, U.P
²Research Supervisor, Technology and Computer Science, The Glocal University, Mirzapurpole, Saharanpur, U.P
ABSTRACT
In this data that are kept in the cloud to take many advantages that are made available by the features of cloud computing. These advantages include storage management, ubiquitous access, cost reductions in hardware installation, software licensing, and service management. The cloud computing platform offers its customers a variety of processing and storage options. One of the delivery models that the cloud uses is called Infrastructure as a Service (IaaS), and it is used to supply cloud storage. All of these advantages drive enterprises to store their data in the cloud. The fact that the data is kept on the cloud (a distant server) which is shared by many users and the data is not under the direct control of the data owner raises some severe concerns about the security of the data that is stored. The integrity, confidentiality, and availability of the data are all components of data security. In this work, we have explored the data security concerns that develop as a result of the nature of cloud computing, namely in terms of confidentiality, integrity, and availability, and we have presented numerous solutions that are purposed by the researcher to counteract these security difficulties. We have high hopes that the researcher will be able to better grasp the current approach that is used to secure cloud storage after reading this study, and we believe that in the future, even more secure cloud storage strategies will be developed.
Keywords – Cloud storage, Symmetric key cryptography, Proxy re-encryption, Asymmetric key cryptography. Secure data sharing, Confidentiality, Integrity, availability.
CYBERSECURITY CONCERNS, DIFFICULTIES, AND SOLUTIONS FOR SOCIAL MEDIA PLATFORMS
¹Mahesh Pal and ²Prof. Dr. Bhupendra Kumar
¹Research Scholar, Technology and Computer Science, The Glocal University, Mirzapurpole, Saharanpur, U.P
²Research Supervisor, Technology and Computer Science, The Glocal University, Mirzapurpole, Saharanpur, U.P
ABSTRACT
The Internet is one of the areas of technical infrastructure development that is developing the fastest in the current socioeconomic climate. The digital world is seriously threatened by the rise in cyberattacks during the last ten years. Given the explosive growth in the usage of social media by both individuals and organizations, this paper focuses on the cybersecurity concerns surrounding social networking sites (SNS). Applications for social networking sites include branding, social e-commerce, and digital marketing. One of the biggest challenges is that the majority of users are unaware of the risks, and their ignorance contributes to an increase in cybercrimes. All these issues would form a part of the paper. The security concerns and challenges on SNS like identity misuse, malware, phishing attacks and third party application threats have also been discussed separately. While highlighting the government initiatives to curb this serious issue, the paper also suggests some appropriate solutions which can be adopted by the individual users as well as the government in the collaboration with private sector for a cyber-safe digital world.
Keywords – Cyber Security, Social Networking Sites, Security issues, Cyber Crimes, Digital world, Cyber attacks, security awareness, National Cyber Security Policy 2013.
SAFETY AND TOXICITY EVALUATION OF FICUS LONGIFOLIA SABRE TREE
¹Madhur Kant and ²Dr. Rakesh Kumar Meel
¹School of Pharmacy, Glocal University, Saharanpur, UP.
²School of Pharmacy, Glocal University, Saharanpur, UP.
ABSTRACT
The goal of this research investigation was to conduct pharmacological research on Ficus longifolia for a number of different pharmacological studies. Flavanoids, steroids, terpenes, phenolics, glycosides, alkaloids, amino acids, and reducing sugars were found to be phytoconstituents in portions of the sabre tree. Low ash readings showed that the plant material was uncontaminated, and low ash values that were insoluble in acid showed that there was no sand or siliceous debris present. TPC and TFC studies revealed that whereas TPC concentration in EERFL was low, it was high in EELFL and EEAPFL. EELFL demonstrated the strongest NO scavenging activity and antioxidant activity that was also directly correlated with dosage. There was no death in toxicity studies—not even at doses of 2000 mg/kg b. wt. Thus, it was determined that EELFL, EEAPFL, and EERFL had a very large safety margin and were categorised as non-toxic constituents. It is suggested that more study be done to identify and define the pharmacologically active components of the Ficus longifolia extracts EELFL, EEAPFL, and EERFL.
Keywords – Loss on Drying (LOD), Total phenolic content (TPC), Total flavonoid content (TFC), ethanolic extract of leaves of Ficus longifolia (EELFL), ethanolic extract of aerial parts of Ficus longifolia (EEAPFL), and ethanolic extract of roots of Ficus longifolia (EERFL).
STUDY OF DIURETIC ACTIVITY OF MEDICINAL PLANTS: Chlorophytum borivilianum AND Asparagus racemosus
¹Mageshwari R and ²Prof. (Dr.) Rahul Kumar Raj
¹Research Scholar, School of Pharmacy, Glocal University Saharanpur (U.P)
²Research Supervisor, School of Pharmacy, Glocal University Saharanpur (U.P)
ABSTRACT
The Diuretic activity of Chlorophytum borivilianum and Asparagus racemosus leaves was studied. The fractions of ethyl acetate, methanol showed significant increase in the urine elimination, while benzene fraction doesn’t show diuresis. All the groups were comparing to control group, frusemide was used as reference standard drug in this screening activity. The phytochemical screening study showed the presence of flavonoids, saponins, terpenoids, and steroid content in both the plants extract. The diuretic effect in all the extract may be due to phytochemicals present in the fractions except benzene fraction of A. indicum.
Keywords – Asparagus racemosus leaves, expectorant, Ethyl acetate, traditional, frusemide.